In recent years, attention has increasingly focused on herbal medicines and their bioactive components attributed to their multi-target pharmacological activity and low side effects. Oridonin is a natural diterpenoid extracted from the traditional Chinese herb and is one of the main active components of Rabdosia rubescens. Modern pharmacological studies have shown that oridonin has anti-tumor, anti-bacterial, anti-inflammatory, anti-oxidant, cardiovascular protective, immunomodulatory, and other effects. Based on the published literature in recent years, we outline the pharmacological activities of oridonin, aiming to provide a theoretical basis for the design and development of new oridonin-based drugs, as well as to facilitate the process of oridonin for clinical use.

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冬凌草甲素药理活性研究进展及未来发展潜力

近年来，由于具有多靶点药理活性和低副作用，越来越多的注意力集中在草药及其生物活性成分上。冬凌草甲素是从传统中草药中提取的天然二萜类化合物，是冬凌草的主要活性成分之一。现代药理研究表明，冬凌草甲素具有抗肿瘤、抗菌、抗炎、抗氧化、心血管保护、免疫调节等作用。基于近年来发表的文献，我们概述了冬凌草甲素的药理活性，旨在为冬凌草甲素类新药的设计和开发提供理论依据，同时促进冬凌草甲素的临床应用进程。