The reaction of [1.1.1]propellane with di-tert-butyl azodicarboxylate and phenylsilane in the presence of Mn(dpm)₃ to give di-tert-butyl 1-(bicyclo[1.1.1]pentan-1-yl)hydrazine-1,2-dicarboxylate is described. Subsequent deprotection gives 1-bicyclo[1.1.1]pentylhydrazine followed by reduction to give 1-bicyclo[1.1.1]pentylamine. The reported route marks a significant improvement over the previous syntheses of 1-bicyclo[1.1.1]pentylamine in terms of scalability, yield, safety, and cost.

中文翻译：

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通过氢酰肼化反应可扩展合成1-双环[1.1.1]戊胺

[1.1.1]螺桨烷与二的反应叔丁基偶氮二羧酸酯和苯基硅烷中的Mn（DPM）的存在₃，得到二-叔丁基1-（二环[1.1.1]戊-1-基）肼描述了-1，2-二羧酸酯。随后的脱保护得到1-双环[1.1.1]戊基肼，然后还原得到1-双环[1.1.1]戊基胺。在可扩展性，产率，安全性和成本方面，所报道的路线标志着对先前的1-双环[1.1.1]戊胺合成的显着改进。