Field-effect transistor (FET) biosensor has received widespread attention due to their unique high-sensitivity properties. In conventional FET biosensors, the complicated interaction between the sample solution and the semiconductor channel always results in poor stability. Especially for FET-based pH sensors, the interface failure caused by the harsh acid-base working environment makes accurate, continuous, and low hysteresis pH measurement quite challenging. Here, we report a carbon nanotube (CNT)-FET pH sensor with enhanced environmental stability by introducing HfO₂ film into the gate insulator. The proposed devices show desired immunity to environmental interference including various chemical and physical factors. More importantly, we verified the feasibility of this CNT-FET device for continuous pH sensing, which demonstrates a sensitivity of 67.62 mV/pH, a wide pH range of 1.34–12.68, and low hysteresis of 500 pA with pH switching loops of 4.22–10.24. This work not only realizes a high-performance pH sensor but also paves the way for the development of FET biosensors with high environmental stability, which is of great significance for FET biosensors to maintain normal working performance in complex systems.

场效应晶体管（FET）生物传感器由于其独特的高灵敏度特性而受到广泛关注。在传统的 FET 生物传感器中，样品溶液与半导体通道之间复杂的相互作用总是导致稳定性差。特别是对于基于 FET 的 pH 传感器，恶劣的酸碱工作环境导致的接口故障使得准确、连续和低滞后 pH 测量非常具有挑战性。在这里，我们报告了一种碳纳米管 (CNT)-FET pH 传感器，它通过引入 HfO _{2增强了环境稳定性}薄膜进入栅极绝缘体。所提出的设备显示出对包括各种化学和物理因素在内的环境干扰的所需免疫力。更重要的是，我们验证了这种 CNT-FET 器件用于连续 pH 传感的可行性，它展示了 67.62 mV/pH 的灵敏度、1.34–12.68 的宽 pH 范围和 500 pA 的低滞后，以及 4.22– 的 pH 切换回路。 10.24。该工作不仅实现了高性能的pH传感器，也为开发具有高环境稳定性的FET生物传感器铺平了道路，对于FET生物传感器在复杂系统中保持正常工作性能具有重要意义。