In the last decade, the field of oligonucleotide therapeutics has matured, with the regulatory approval of several single-stranded and double-stranded RNA drugs. In this Perspective, I discuss enabling developments and likely future directions in the field from the perspective of oligonucleotide chemistry.

中文翻译：

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寡核苷酸治疗领域药物化学的未来方向

在过去十年中，寡核苷酸治疗领域已经成熟，一些单链和双链 RNA 药物获得监管批准。在这个观点中，我从寡核苷酸化学的角度讨论了该领域的有利发展和可能的未来方向。