Galvanic Redox Potentiometry for Fouling-Free and Stable Serotonin Sensing in a Living Animal Brain,Angewandte Chemie International Edition

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Galvanic Redox Potentiometry for Fouling-Free and Stable Serotonin Sensing in a Living Animal Brain
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2023-01-23 , DOI: 10.1002/anie.202212458
Fenghui Zhu ₁ , Yifei Xue ₁ , Wenliang Ji ₁ , Xin Li ₁ , Wenjie Ma _{2,

3} , Ping Yu _{2,

3} , Ying Jiang ₁ , Lanqun Mao ₁

Affiliation

A fouling-free, highly stable, and sensitive sensor based on galvanic redox potentiometry (GRP) is presented to study serotonin dynamics in the living guinea pig brain. The GRP sensor could be used to study many other neurochemicals with similar serious fouling issues in living biosystems, promoting the understanding of brain function and neurological diseases at the molecular level.

中文翻译：

用于活体动物大脑中无污染和稳定血清素传感的电流氧化还原电位法

提出了一种基于电流氧化还原电位法 (GRP) 的无污染、高度稳定且灵敏的传感器，用于研究活豚鼠大脑中的血清素动力学。GRP 传感器可用于研究活体生物系统中具有类似严重污染问题的许多其他神经化学物质，促进在分子水平上对脑功能和神经系统疾病的理解。

更新日期：2023-01-23

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