影响 1550 nm 掺铒点阵光热解激光治疗个别萎缩性痤疮疤痕疗效的临床因素,Dermatology and Therapy

当前位置： X-MOL 学术 › Dermatol. Ther. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

影响 1550 nm 掺铒点阵光热解激光治疗个别萎缩性痤疮疤痕疗效的临床因素
Dermatology and Therapy ( IF 3.5 ) Pub Date : 2023-01-12 , DOI: 10.1007/s13555-022-00887-8
Soo Ran Lee ₁ , Soyun Cho ₁

Affiliation

介绍

尽管非剥脱点阵换肤经常用于治疗萎缩性痤疮疤痕，但很少有研究探讨影响非剥脱点阵激光治疗个别萎缩性痤疮疤痕类型（冰锥疤痕、滚动疤痕和棚车疤痕）有效性的临床因素。在此，我们使用客观评估工具评估了影响非剥脱点阵激光治疗个别萎缩性痤疮疤痕类型效果的临床因素。

方法

对 31 例接受 1550 nm 掺铒点阵激光治疗萎缩性痤疮疤痕的患者进行回顾性分析。使用照片对冰锥疤痕、滚动疤痕和棚车疤痕进行计数，并计算痤疮疤痕减少效率（ASRE％；痤疮后疤痕计数相对于基线计数的减少百分比）。

结果

在最后一次治疗结束时，每种疤痕类型的中位数计数显着减少。棚车疤痕的反应比滚动疤痕（ASRE 40.6%，p = 0.017）和冰镐疤痕（ASRE 19.1%，p = 0.010）反应更好（中位 ASRE 59.2%）。联合使用异维A酸可改善ASRE，并显着改善冰锥疤痕。25 岁或以下的患者表现出更高的 ASRE，棚车疤痕有更大的改善。

结论

1550 nm 点阵激光治疗萎缩性痤疮疤痕对于年轻且同时服用异维A酸的患者更有效。

"点击查看英文标题和摘要"

Clinical Factors Affecting the Effectiveness of 1550-nm Erbium-Doped Fractional Photothermolysis Laser for Individual Atrophic Acne Scar Types

Introduction

Although non-ablative fractional resurfacing is frequently used for atrophic acne scars, few studies have examined clinical factors affecting the effectiveness of non-ablative fractional laser in individual atrophic acne scar types (icepick, rolling, and boxcar scars). Herein, we evaluated the clinical factors affecting the effect of non-ablative fractional laser for individual atrophic acne scar types using objective assessment tools.

Methods

Thirty-one patients who had been treated by 1550-nm erbium-doped fractional laser for atrophic acne scars were retrospectively reviewed. Icepick, rolling, and boxcar scars were counted using photographs, and acne scar reduction efficiency (ASRE%; the percentage reduction of post-acne scar count from baseline counts) was calculated.

Results

The median count of each scar type was significantly reduced at the end of the final session. Boxcar scars responded better (median ASRE 59.2%) than rolling (ASRE 40.6%, p = 0.017) and icepick scars (ASRE 19.1%, p = 0.010). Concomitant isotretinoin use resulted in a greater ASRE and a significantly greater improvement in icepick scars. Patients aged 25 years or younger showed a higher ASRE, with a greater improvement in boxcar scars.