An entropy-driven DNA nanomachine for microRNA detection using a personal glucose meter,Chemical Communications

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An entropy-driven DNA nanomachine for microRNA detection using a personal glucose meter
Chemical Communications ( IF 4.3 ) Pub Date : 2023-01-06 , DOI: 10.1039/d2cc06479k
Qing Wang ₁ , Yuqiu He ₁ , Shizhen He ₁ , Shanshan Yu ₁ , Yuqian Jiang ₁ , Fuan Wang _{1,

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Affiliation

Herein, we developed a reliable and portable biosensor (TDR-PGM nanomachine) for the sensitive detection of microRNA by integrating an efficient toehold-mediated strand displacement reaction module (TDR) and a personal glucose meter (PGM). The system provides a versatile methodology for microRNA detection in real samples and holds broad prospects in point-of-care diagnosis.

中文翻译：

用于使用个人血糖仪检测 microRNA 的熵驱动 DNA 纳米机器

在此，我们开发了一种可靠且便携式的生物传感器（TDR-PGM 纳米机器），通过集成高效的立足点介导的链置换反应模块 (TDR) 和个人血糖仪 (PGM) 来灵敏检测 microRNA。该系统为实际样本中的 microRNA 检测提供了一种通用的方法，并在即时诊断中具有广阔的前景。

更新日期：2023-01-06

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