The on-site detection of hydrogen peroxide (H₂O₂) is important for maintaining food safety as the ingestion of H₂O₂ can lead to serious pathological conditions. However, most reported fluorescent probes require a fluorometer to ensure readable signal output and reliable detection result. Consequently, the fluorescent detection of H₂O₂ can be realized only within a standard laboratory setting. Herein, we report a novel supramolecular strategy that can successfully convert the typical off-on response to H₂O₂ into a ratiometric response, which allows the on-site detection of H₂O₂ when used in conjunction with a smartphone-based 3D-printed miniaturized testing system. This method has acceptable sensitivity, good anti-interference ability, and desirable accuracy compared to a standard detection method. More importantly, this portable ratiometric method can be used to detect H₂O₂ residue in commercial milk samples with the simple testing apparatuses.

过氧化氢 (H ₂ O ₂ ) 的现场检测对于维护食品安全非常重要，因为摄入 H ₂ O ₂会导致严重的病理状况。然而，大多数报道的荧光探针需要荧光计来确保可读的信号输出和可靠的检测结果。因此，H ₂ O ₂的荧光检测只能在标准实验室环境中实现。_{在此，我们报告了一种新型超分子策略，它可以成功地将对 H 2} O ₂的典型关-开响应转化为比例响应，从而实现 H ₂ O ₂的现场检测当与基于智能手机的 3D 打印微型测试系统结合使用时。与标准检测方法相比，该方法具有可接受的灵敏度、良好的抗干扰能力和理想的准确性。更重要的是，这种便携式比率法可以通过简单的测试设备检测商业牛奶样品中的H ₂ O ₂残留。