由 Syneresis 引导的坚韧、透明和光滑的 PVA 水凝胶,Small

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由 Syneresis 引导的坚韧、透明和光滑的 PVA 水凝胶
Small ( IF 13.0 ) Pub Date : 2023-01-02 , DOI: 10.1002/smll.202206819
Desheng Liu _{1,

2} , Yufei Cao ₃ , Pan Jiang ₁ , Yixian Wang ₄ , Yaozhong Lu ₁ , Zhongying Ji _{1,

5} , Xiaolong Wang _{1,

2,

5} , Weimin Liu _{1,

2}

Affiliation

光滑透明的聚乙烯醇 (PVA) 水凝胶具有机械强度，在人造生物软组织、柔性可穿戴电子产品和植入式生物医学设备中具有广泛的应用。然而，目前的大多数 PVA 水凝胶都无法整合这些特性，从而影响了其在生物和工程应用中的性能。为了实现这一目的，本文提出了一种新的策略，即 PVA 的盐析后脱水，以实现机械坚固且高度透明的光滑 PVA 水凝胶。首先进行 PVA 溶胶的脱水收缩以形成高度致密和透明的 PVA 聚合物网络，然后盐析效应调节聚合物链的聚集以快速诱导相分离和结晶。^-3，分别。为了揭示潜力，展示了结合卓越润滑、抗蛋白质粘附、生物相容性和载药功能的 PVA 隐形眼镜。该策略为开发机械坚固、透明和水合的水凝胶提供了一条简单而新的途径，展示了其在生物医学和可穿戴设备中的潜力。

"点击查看英文标题和摘要"

Tough, Transparent, and Slippery PVA Hydrogel Led by Syneresis

Slippery and transparent polyvinyl alcohol (PVA) hydrogels with mechanical robustness exhibit broad applications in artificial biological soft tissues, flexible wearable electronics, and implantable biomedical devices. Most of the current PVA hydrogels, however, are unable to integrate these features, which compromises its performance in biological and engineering applications. To achieve such purpose, herein, a novel tactic is proposed, salting-out-after-syneresis of PVA, to realize a mechanically robust and highly transparent slippery PVA hydrogel. The syneresis of PVA sol is first conducted to form highly dense and transparent PVA polymer networks, then the salting-out effect tunes the aggregation of the polymer chains to rapidly induce the phase separation and crystallization. The resultant hydrogels show the transparency up to 98% in the visible region, the tribological coefficient down to 0.0081, and the excellent mechanical properties with strength, modulus, and toughness of 26.72 ± 1.05, 6.66 ± 0.29 MPa, and 55.21 ± 1.62 MJ m⁻³, respectively. To reveal the potentials, PVA contact lens that combine remarkable lubrication, anti-protein adhesion, biocompatibility, and drug-loading functions are demonstrated. This strategy provides a simple and new avenue for developing the mechanically robust, transparent, and hydrated hydrogels, showing the potential in biomedicine and wearable devices.

更新日期：2023-01-02

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