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Enhanced production of high-value polyunsaturated fatty acids (PUFAs) from potential thraustochytrid Aurantiochytrium sp.
Bioresource Technology ( IF 9.7 ) Pub Date : 2022-12-26 , DOI: 10.1016/j.biortech.2022.128536
Ajeet Singh Chauhan , Anil Kumar Patel , Chiu-Wen Chen , Jo-Shu Chang , Philippe Michaud , Cheng-Di Dong , Reeta Rani Singhania

Due to growing health concerns, the urban population is utterly inclined towards a healthy lifestyle and incorporated nutritional food supplements to lower common health risks. The ω-3 and ω-6 PUFAs consumption is increasing, hence alternative commercial production is essentially developed. The microbial source is an emerging platform to overcome the global demand for omega PUFAs. Marine oleaginous protist Aurantiochytrium sp. found a potential source to produce substantial DHA and SFA. The objective of the present research was to enhance the PUFA yield by optimizing maximum tolerable glucose concentration with a suitable nitrogen ratio (10:1). The maximum lipid and DHA yield and content were determined 4.30, 1.34 g/L, and 62.4, 33.49 % of total biomass and lipid at 30 g/L glucose respectively, which is one of among highest reported, however relative PUFA was maximum 46.97 % (DHA) in total lipid at 10 g/L glucose. Remaining 42–53.6 % SFA could be used for biodiesel.

中文翻译:


增强潜在 thraustochytrid Aurantiochytrium sp 的高价值多不饱和脂肪酸 (PUFA) 的生产。



由于对健康的担忧日益严重,城市人口完全倾向于健康的生活方式,并加入营养食品补充剂以降低常见的健康风险。ω-3 和 ω-6 PUFA 的消费量正在增加,因此基本上开发了替代商业生产。微生物来源是克服全球对 omega PUFA 需求的新兴平台。海洋含油原生生物 Aurantiochytrium sp. 发现了产生大量 DHA 和 SFA 的潜在来源。本研究的目的是通过以合适的氮比例 (10:1) 优化最大可耐受葡萄糖浓度来提高 PUFA 产量。在 30 g/L 葡萄糖下,脂质和 DHA 的最大产量和含量分别为总生物量和 33.49 % 的 4.30、1.34 g/L 和 62.4、33.49 %,这是报道的最高水平之一,但相对 PUFA 在 10 g/L 葡萄糖时总脂质中的最大 46.97% (DHA)。剩余的 42-53.6 % SFA 可用于生物柴油。
更新日期:2022-12-26
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