Stereoselective Construction of Chiral Linear [3]Catenanes and [2]Catenanes,Journal of the American Chemical Society

当前位置： X-MOL 学术 › J. Am. Chem. Soc. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Stereoselective Construction of Chiral Linear [3]Catenanes and [2]Catenanes
Journal of the American Chemical Society ( IF 14.4 ) Pub Date : 2022-12-22 , DOI: 10.1021/jacs.2c12027
Zheng Cui ₁ , Qiu-Shui Mu ₁ , Xiang Gao ₁ , Guo-Xin Jin _{1,

2}

Affiliation

We have successfully constructed a chiral linear [3]catenane stereoselectively by coordination-driven self-assembly using a ditopic monodentate ligand containing l-valine residues with a binuclear half-sandwich organometallic rhodium(III) unit. Furthermore, by increasing the steric hindrance of the amino acid residues in the ligand, a chiral [2]catenane was obtained, which can be regarded as the factor catenane of the chiral linear [3]catenane from a topological viewpoint. Notably, the resulting molecular catenanes all exhibit complex coconformational mechanical helical chirality and planar chirality ascribed to the point chirality of the ligands. Linear [3]catenanes and [2]catenanes with the opposite chirality can be obtained by using ligands containing the corresponding d-amino acid residues, which have been confirmed by single-crystal X-ray diffraction, NMR, mass spectrometry, and circular dichroism spectroscopy.

中文翻译：

手性线性 [3] 链烷和 [2] 链烷的立体选择性构建

我们使用含有l-缬氨酸残基和双核半夹心有机金属铑 (III) 单元的双位单齿配体，通过配位驱动的自组装，成功地立体选择性地构建了手性线性 [3] 链烯。此外，通过增加配体中氨基酸残基的空间位阻，得到了手性[2]链烷，从拓扑学的角度看，它可以看作是手性线性[3]链烷的因子链烷。值得注意的是，由此产生的分子链均表现出复杂的共构机械螺旋手性和平面手性，这归因于配体的点手性。使用含有相应d的配体可以获得具有相反手性的线性[3]链烷和[2]链烷-氨基酸残基，经单晶X射线衍射、核磁共振、质谱、圆二色光谱等证实。

更新日期：2022-12-22

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南