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Disruption of Zinc Homeostasis by a Novel Platinum(IV)-Terthiophene Complex for Antitumor Immunity
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2022-12-22 , DOI: 10.1002/anie.202216917
Xuxian Su 1 , Bin Liu 1 , Wen-Jin Wang 1 , Kun Peng 1 , Bing-Bing Liang 1 , Yue Zheng 1 , Qian Cao 1 , Zong-Wan Mao 1
Affiliation  

We developed a novel cyclometalated PtIV-terthiophene complex as the first metal-based zinc homeostatic medicine that regulates zinc homeostasis to activate antitumor immunity.

中文翻译:

一种用于抗肿瘤免疫的新型铂 (IV)-三联噻吩复合物破坏锌稳态

我们开发了一种新型环金属化 Pt IV -三联噻吩络合物作为第一种基于金属的锌稳态药物,可调节锌稳态以激活抗肿瘤免疫。
更新日期:2022-12-22
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