3-Isothiocyanato oxindoles are a class of important building blocks which have been widely used in the synthesis of structurally diverse enantioenriched spirooxindoles. In this short review, it is attempted to cover the recent synthetic aspects of 3-isothiocyanato oxindoles participated cascade cyclizations in the last few years (i.e., from 2017 to 2022), with an emphasis on formal [3+2] cycloaddition reactions.

1 Introduction

2 Organocatalyzed Formal [3+2] Cycloaddition of 3-Isothiocyanato Oxindoles

3 Lewis Acid Catalyzed Formal [3+2] Cycloaddition of 3-Isothiocyanato Oxindoles

4 Conclusions

中文翻译：

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3-异硫氰酸根羟吲哚的不对称形式 [3+2] 环加成反应：更新

3-异硫氰酸基羟吲哚是一类重要的结构单元，已广泛用于合成结构多样的对映体富集的螺羟吲哚。在这篇简短的综述中，它试图涵盖最近几年（即，从 2017 年到 2022 年）参与级联环化的 3-异硫氰酸根羟基化合物的最新合成方面，重点是正式的 [3+2] 环加成反应。

1 简介

2 有机催化的3-异硫氰酸根羟吲哚的甲醛[3+2]环加成反应

3 路易斯酸催化3-异硫氰酸根羟吲哚的甲醛[3+2]环加成反应

4。结论