<br>量化使用灰和沙子作为洗手剂所实现的病毒减少效果,American Journal of Tropical Medicine and Hygiene

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量化使用灰和沙子作为洗手剂所实现的病毒减少效果
American Journal of Tropical Medicine and Hygiene Pub Date : 2022-12-19 , DOI: 10.4269/ajtmh.22-0581
Winnie Zambrana ₁ , Jingyan Tong ₁ , Claire E Anderson ₁ , Alexandria B Boehm ₁ , Marlene K Wolfe _{1,

2}

Affiliation

摘要。世界卫生组织建议用肥皂和水洗手 20 至 40 秒。在没有肥皂的环境中，人们会使用灰或沙子来洗手，但它们作为洗手材料的功效尚未得到充分研究。本研究的目的是量化使用灰和沙作为洗手剂去除病毒的效果，并将其功效与通常推荐的洗手方法进行比较。我们进行了一项志愿者研究，以估计两种洗手剂（灰和水、沙子和水）和两个时间点（5 秒和 20 秒）的六种洗手条件后手上模型病毒 Phi6 和 MS2 的对数减少值 (LRV) ，以及两种洗手剂（肥皂和水，以及仅水），同一个时间点（20 秒）。噬菌斑测定用于测量传染性病毒的减少。使用任何一种洗手剂洗手 20 秒，其 LRV 均高于美国食品和药物管理局针对这两种病毒的 2 个对数减少标准。对于这两种病毒，肥皂和水清洗 5 秒的 LRV (2.7–4.8) 显着高于用灰和水 (2.0–2.8) 或沙子和水 (1.8–2.7) 清洗 5 秒，而水仅导致显着更高的 LRV (2.8) 高于仅 MS2 的所有灰分 (2.0–2.6) 和沙子 (1.8–2.4) 条件。这些结果表明，使用灰或沙子作为洗手剂可以有效减少病毒，但可能不如肥皂有效，特别是在较短时间使用时。进一步的研究应该调查在现实环境中使用灰和沙子作为洗手剂。

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Quantifying the Viral Reduction Achieved Using Ash and Sand as Handwashing Agents

ABSTRACT. The WHO recommends handwashing with soap and water for 20–40 seconds. In settings where soap is not available, ash or sand is used for handwashing, yet their efficacy as handwashing materials is underresearched. The purpose of this study was to quantify the removal of viruses using ash and sand as handwashing agents, and compare their efficacy to commonly recommended handwashing methods. We performed a volunteer study to estimate the log reduction value (LRV) of model viruses Phi6 and MS2 on hands after six handwashing conditions: two handwashing agents (ash and water, and sand and water) with two time points (5 and 20 seconds), and two handwashing agents (soap and water, and water only) with one time point (20 seconds). Plaque assays were used to measure infectious virus reduction. Handwashing with any of the handwashing agents for 20 seconds resulted in a greater LRV than the 2-log reduction U.S. Food and Drug Administration criteria for both viruses. Soap and water resulted in a significantly greater LRV (2.7–4.8) than washing with ash and water (2.0–2.8) or sand and water (1.8–2.7) for 5 seconds for both viruses, and water only resulted in a significantly higher LRV (2.8) than all ash (2.0–2.6) and sand (1.8–2.4) conditions for MS2 only. These results suggest that using ash or sand as handwashing agents can be efficacious in reducing viruses but may be less efficacious than soap, especially when used for shorter durations. Further research should investigate the use of ash and sand as handwashing agents in real-world settings.

更新日期：2022-12-19

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