Photocatalytic Generation of Hydrogen Radical (H⋅) with GSH for Photodynamic Therapy,Angewandte Chemie International Edition

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Photocatalytic Generation of Hydrogen Radical (H⋅) with GSH for Photodynamic Therapy
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2022-12-20 , DOI: 10.1002/anie.202214991
Jinlei Peng ₁ , Ke Du ₁ , Jian Sun _{1,

2} , Xianli Yang ₃ , Xia Wang ₁ , Xiaoran Zhang ₁ , Gang Song _{1,

2} , Fude Feng ₁

Affiliation

An organic photocatalytic hydrogen radical (H⋅) generator is activated by glutathione (GSH) for enhanced photodynamic therapy (PDT) against normoxic tumor cells via a hybrid ferroptosis-apoptosis pathway. H⋅ therapy is also effective in fighting tumors under hypoxic conditions through biological reduction.

中文翻译：