A cyclohexane (CY)/isopropanol (IPA)/water mixture has complex thermodynamic properties with three binary azeotropes and one ternary azeotrope. A configuration of double-column reactive–extractive distillation (DCRED) is suitable to be used for the separation of this mixture with ethylene oxide (EO) as the dehydrating agent. Taking advantage of a large liquid–liquid envelope in the ternary map of this mixture, two novel process configurations are proposed in this study to separate the mixture with the percentage of water to total feed ranging from 10 to 90 mol %. A process configuration that includes a pretreatment section followed by a DCRED section (P-DCRED) was proven to be efficient in separating the mixture with the percentage of water ranging from 50 to 90 mol %, while only the DCRED process configuration showed its superiority when dealing with the mixture with the percentage of water ranging from 10 to 40 mol %. Compared to the traditional extractive distillation (ED) and another process of ED coupled with pervaporation (PV) in the recent literature, the novel processes proposed in this study can save a total annual cost (TAC) of 20 to 80%.

中文翻译：

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用于分离具有不同进料组成的环己烷/异丙醇/水混合物的混合反应-萃取蒸馏系统的新工艺开发

环己烷 (CY)/异丙醇 (IPA)/水混合物具有复杂的热力学性质，具有三种二元共沸物和一种三元共沸物。双塔反应萃取蒸馏 (DCRED) 的配置适用于以环氧乙烷 (EO) 作为脱水剂分离该混合物。利用该混合物三元图中的大液-液包络，本研究提出了两种新的工艺配置来分离混合物，其中水占总进料的百分比为 10 至 90 mol%。包括预处理部分和紧随其后的 DCRED 部分 (P-DCRED) 的工艺配置被证明可有效分离含水百分比为 50 至 90 mol% 的混合物，而只有 DCRED 工艺配置在处理水百分比为 10 至 40 mol% 的混合物时显示出其优势。与最近文献中传统的萃取蒸馏 (ED) 和另一种 ED 与渗透蒸发 (PV) 相结合的工艺相比，本研究提出的新工艺可以节省 20% 至 80% 的年度总成本 (TAC)。