Recent progress on photodynamic therapy and photothermal therapy,Bulletin of the Korean Chemical Society

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Recent progress on photodynamic therapy and photothermal therapy
Bulletin of the Korean Chemical Society ( IF 2.3 ) Pub Date : 2022-12-15 , DOI: 10.1002/bkcs.12655
Heejeong Kim ₁ , Mengyao Yang ₁ , Nahyun Kwon ₁ , Moonyeon Cho ₁ , Jingjing Han ₁ , Rui Wang ₁ , Sujie Qi ₁ , Haidong Li ₂ , Van‐Nghia Nguyen ₁ , Xingshu Li ₃ , Hong‐Bo Cheng ₄ , Juyoung Yoon ₁

Affiliation

Noninvasive treatments for terminal cancer patients constitute a new trend in tumor treatment. Therefore, phototherapy, including photodynamic therapy (PDT) and photothermal therapy (PTT), has attracted considerable interest. Light and a photosensitizer (PS) are employed in both treatment methods. For PDT, the PS generates reactive oxygen species (ROS) when exposed to light, whereas for PTT, the PS generates heat. In this regard, the systematic design of new PSs has become an active area of phototherapy research in an effort to solve the problems associated with conventional PSs. In the past decade, activatable and heavy-atom-free PSs have become significant research areas. Therefore, we discuss our recent contributions to the PDT and PTT in this account.

中文翻译：

光动力疗法和光热疗法的最新进展

晚期癌症患者的无创治疗是肿瘤治疗的新趋势。因此，包括光动力疗法（PDT）和光热疗法（PTT）在内的光疗法引起了人们的极大兴趣。两种处理方法均采用光和光敏剂 (PS)。对于 PDT，PS 在暴露于光时会产生活性氧 (ROS)，而对于 PTT，PS 会产生热量。在这方面，新 PS 的系统设计已成为光疗研究的一个活跃领域，以努力解决与传统 PS 相关的问题。在过去的十年中，可激活和无重原子的 PS 已成为重要的研究领域。因此，我们在此帐户中讨论我们最近对 PDT 和 PTT 的贡献。

更新日期：2022-12-15

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