The fungal pathogen receptor dectin-1 instructs the development of non-pathogenic TH17 cells via TGFβ activation. This process requires strict control of the expression of type I interferon to ensure a delicate balance in the expression of its effector genes that control the release of active TGFβ.

中文翻译：

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I 型干扰素作为 dectin-1 触发非致病性 TH17 细胞发育的抗真菌作用

真菌病原体受体 dectin-1 通过 TGFβ 激活指导非致病性 TH17 细胞的发育。这个过程需要严格控制 I 型干扰素的表达，以确保控制活性 TGFβ 释放的效应基因表达的微妙平衡。