The uncontrolled oxidative decomposition of electrolyte while operating at high potential (> 4.2 V vs Li/Li⁺) severely affects the performance of high-energy density transition metal oxide-based materials as cathodes in Li-ion batteries. To restrict this degradative response of electrolyte species, the need for functional molecules as electrolyte additives that can restrict the electrolytic decomposition is imminent. In this regard, bio-derived molecules are cost-effective, environment friendly, and non-toxic alternatives to their synthetic counter parts. Here, we report the application of microbially synthesized 2,5-dimethyl-3,6-bis(4-aminobenzyl)pyrazine (DMBAP) as an electrolyte additive that stabilizes high-voltage (4.5 V vs Li/Li⁺) LiNi_1/3Mn_1/3Co_1/3O₂ cathodes. The high-lying highest occupied molecular orbital of bio-additive (DMBAP) inspires its sacrificial in situ oxidative decomposition to form an organic passivation layer on the cathode surface. This restricts the excessive electrolyte decomposition to form a tailored cathode electrolyte interface to administer cyclic stability and enhance the capacity retention of the cathode.

^{在高电位（> 4.2 V vs Li/Li +} ）下运行时，电解质不受控制的氧化分解严重影响了高能量密度过渡金属氧化物基材料作为锂离子电池阴极的性能。为了限制电解质物质的这种降解反应，迫切需要功能分子作为电解质添加剂来限制电解分解。在这方面，生物衍生分子是其合成对应物的成本效益高、环境友好且无毒的替代品。在这里，我们报告了微生物合成的 2,5-二甲基-3,6-双（4-氨基苄基）吡嗪 (DMBAP) 作为电解质添加剂的应用，可稳定高电压（4.5 V vs Li/Li ⁺）LiNi _{1/ 3}锰_1/3 Co _1/3 O ₂阴极。生物添加剂（DMBAP）的高位最高占据分子轨道激发其原位氧化分解牺牲，在阴极表面形成有机钝化层。这限制了过度的电解质分解，形成定制的阴极电解质界面，以实现循环稳定性并提高阴极的容量保持率。