Commercially available compounds that can be directly used as fluorescent probes will greatly promote the development of fluorescent imaging. Based on our previously work related to nitrogen bridgehead heterocycles, herein, a commercially available compound, 6-chloroimidazo[1,2-a]pyridine-2-carboxylic acid, has been detected for monitoring pH value (3.0–7.0). The probe proves to have high selectivity and sensitivity, brilliant reversibility, and extremely short response time. The real-time imaging of pH changes in yeast was also conducted.

中文翻译：

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用于监测 pH 变化的基于 6-chloroimidazo[1,2-a]pyridine-2-carboxylic 酸的简单且可商购的荧光探针

可直接用作荧光探针的市售化合物将极大地促进荧光成像的发展。基于我们之前与氮桥头杂环化合物相关的工作，本文检测了一种市售化合物 6-氯咪唑并[1,2-a] 吡啶-2-羧酸，用于监测 pH 值 (3.0–7.0)。该探针被证明具有高选择性和灵敏度、出色的可逆性和极短的响应时间。还进行了酵母 pH 变化的实时成像。