Dynamic Covalent Chemistry for Synthesis and Co-conformational Control of Mechanically Interlocked Molecules,European Journal of Organic Chemistry

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Dynamic Covalent Chemistry for Synthesis and Co-conformational Control of Mechanically Interlocked Molecules
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2022-11-15 , DOI: 10.1002/ejoc.202201130
Jingjing Yu ₁ , Marius Gaedke ₁ , Fredrik Schaufelberger ₁

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The efficient synthesis of mechanical bonds is a huge challenge. Dynamic covalent chemistry is one of the most efficient methods for forming rotaxanes, catenanes and molecular knots in high yields. This Review reports recent uses of reversible covalent bonds to synthesize mechanically interlocked molecules, and discusses how dynamic bonds can be used to control motion in interlocked molecular machinery.

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