The recently synthesized 1-chloro-11-oxo-3,4-dihydro-11H-chromeno[4,3-b]quinoline-2-carboxaldehyde (1) was efficiently utilized as a key precursor to construct a diversity of polyfused systems containing chromeno[4,3-b]quinoline. Reaction of compound 1 with some substituted hydrazines afforded pyrazoles annulated chromeno[4,3-b]quinoline. Treatment of compound 1 with a diversity of 1,3-N,N-binucleophiles led to pyrimidines annulated chromeno[4,3-b]quinoline. In addition, a diversity of fused pyridines annulated chromeno[4,3-b]quinoline were synthesized from condensation of compound 1 with a variety of 1,3-C,N-binucleophiles. Finally, the reactivity of compound 1 was tested towards a diversity of 1,4-binucleophilic reagents. Structures of the new compounds were established using spectral and analytical data.

中文翻译：

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一些新型杂环铬烯[4,3-

最近合成的 1-chloro-11-oxo-3,4-dihydro-11 H -chromeno[4,3 - b ]quinoline-2-carboxaldehyde ( 1 )被有效地用作构建多种多融合系统的关键前体含铬烯[4,3- b ]喹啉。化合物1与一些取代的肼反应得到环环化的吡唑[4,3- b ] 喹啉。用多种 1,3 - N , N-双亲核试剂处理化合物1 ，得到嘧啶环化的铬烯基 [4,3- b ] 喹啉。此外，多种稠合吡啶环化了铬烯[4,3- b ]喹啉由化合物1与多种 1,3 -C , N-双亲核试剂缩合合成。最后，测试了化合物1对多种 1,4-双亲核试剂的反应性。新化合物的结构是使用光谱和分析数据建立的。