Progress and gaps of extracellular vesicle-mediated intercellular cargo transfer in the central nervous system,Communications Biology

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Progress and gaps of extracellular vesicle-mediated intercellular cargo transfer in the central nervous system
Communications Biology ( IF 5.2 ) Pub Date : 2022-11-11 , DOI: 10.1038/s42003-022-04050-z
Chun Wan ₁ , Michael H B Stowell ₁ , Jingshi Shen ₁

Affiliation

A fundamentally novel function proposed for extracellular vesicles (EVs) is to transfer bioactive molecules in intercellular signaling. In this minireview, we discuss recent progress on EV-mediated cargo transfer in the central nervous system (CNS) and major gaps in previous studies. We also suggest a set of experiments necessary for bridging the gaps and establishing the physiological roles of EV-mediated cargo transfer.

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