The etiology of peripartum cardiomyopathy (PPCM) is unknown. Therefore, we evaluated the etiology of patients clinically diagnosed with PPCM using endomyocardial biopsy. We studied five patients diagnosed with PPCM following endomyocardial biopsy (age, 28–42 years; mean age, 35 years). Biopsied samples were evaluated using microscopy, including immunostaining and electron microscopy. The pathological findings were as follows: myocardial hypertrophy, myocardial fibrosis, and cell infiltration. Two patients were diagnosed with lymphocytic myocarditis, one with eosinophilic myocarditis, one with hypertensive heart disease, and one with a combination of hypertension and myocarditis. Endomyocardial biopsy suggested that the causes of PPCM were varied and related to myocarditis and myocardial overload due to hypertension.

围产期心肌病（PPCM）的病因尚不清楚。因此，我们使用心内膜心肌活检评估了临床诊断为 PPCM 的患者的病因。我们研究了 5 名经心内膜心肌活检诊断为 PPCM 的患者（年龄，28-42 岁；平均年龄，35 岁）。使用显微镜评估活检样品，包括免疫染色和电子显微镜。病理结果为：心肌肥厚、心肌纤维化、细胞浸润。 2例患者被诊断为淋巴细胞性心肌炎，1例为嗜酸性粒细胞性心肌炎，1例为高血压性心脏病，1例为高血压和心肌炎合并症。心内膜心肌活检提示PPCM的病因多种多样，与心肌炎和高血压引起的心肌超负荷有关。