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Biomimetic Total Syntheses of Linderaspirone A and Bi-linderone and Revisions of Their Biosynthetic Pathways
Organic Letters ( IF 4.9 ) Pub Date : 2011-03-29 00:00:00 , DOI: 10.1021/ol200418e
Haibo Tan 1 , Chao Zheng 1 , Zheng Liu 1 , David Zhigang Wang 1
Affiliation  

Simple exposure to sunlight is sufficient for triggering photochemical [2 + 2] cycloaddition−Cope or radical rearrangement cascades in the naturally occurring methyl linderone, leading to efficient biomimetic total syntheses of linderaspirone A and bi-linderone, two recently discovered bioactive spirocyclopentenedione natural products.

中文翻译:

Linderaspirone A和Bi-linderone的仿生全合成及其生物合成途径的修订

简单地暴露在阳光下足以触发天然存在的甲基羟苯甲砜中的光化学[2 + 2]环加成应付或自由基重排级联反应,从而有效地仿制了最近发现的具有生物活性的螺环戊二烯二酮天然产物linderaspirone A和bi-linderone的仿生全合成。
更新日期:2011-03-29
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