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The bioactivities of sclareol: A mini review.
Frontiers in Pharmacology ( IF 4.4 ) Pub Date : 2022-10-03 , DOI: 10.3389/fphar.2022.1014105
Jianbo Zhou 1 , Xiaofang Xie 2 , Hailin Tang 3 , Cheng Peng 2 , Fu Peng 1
Affiliation  

Sclareol, a diterpene alcohol isolated from the herbal and flavor plant clary sage (Salvia sclarea L.), is far-famed as the predominant ingredient in the refined oil of Salvia sclarea (L.). The empirical medicine of Salvia sclarea L. focused on various diseases, such as arthritis, oral inflammation, digestive system diseases, whereas the sclareol possessed more extensive and characteristic bioactivities, including anti-tumor, anti-inflammation and anti-pathogenic microbes, even anti-diabetes and hypertension. However, there is a deficiency of literature to integrate and illuminate the pharmacological attributes of sclareol based on well-documented investigations. Interestingly, sclareol has been recently considered as the potential candidate against COVID-19 and Parkinson's disease. Accordingly, the bioactive attributes of sclareol in cancer, inflammation, even pharmacochemistry and delivery systems are reviewed for comprehensively dissecting its potential application in medicine.

中文翻译:

香紫苏醇的生物活性:一个小型回顾。

香紫苏醇是一种从草本和风味植物快乐鼠尾草 (Salvia sclarea L.) 中分离出来的二萜醇,是著名的丹参 (L.) 精炼油的主要成分。丹参的实证药物主要针对关节炎、口腔炎症、消化系统疾病等多种疾病,而香紫苏则具有更广泛、更具特色的生物活性,包括抗肿瘤、抗炎、抗病原微生物,甚至抗微生物等。 -糖尿病和高血压。然而,缺乏文献来整合和阐明基于有据可查的研究的香紫苏醇的药理属性。有趣的是,香紫苏醇最近被认为是对抗 COVID-19 和帕金森病的潜在候选药物。因此,香紫苏醇在癌症中的生物活性属性,
更新日期:2022-10-03
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