用于生物电信号监测的具有芯吸透气和多机制粘附的仿生贴片,ACS Applied Materials & Interfaces

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用于生物电信号监测的具有芯吸透气和多机制粘附的仿生贴片
ACS Applied Materials & Interfaces ( IF 8.3 ) Pub Date : 2022-10-19 , DOI: 10.1021/acsami.2c13984
Qian Zhang ₁ , Keju Ji ₁ , Tingwei Huo ₁ , Muhammad Niaz Khan ₂ , Zhuoyang Hu ₁ , Cong Yuan ₁ , Jiahui Zhao ₁ , Jian Chen ₁ , Zhouyi Wang ₁ , Zhendong Dai ₁

Affiliation

可穿戴生物电监测设备可以提供长期的人体健康信息，如心电图等生理信号。它是远程医疗系统的重要组成部分。这些可以为心血管疾病的诊断和治疗提供预测和及时治疗的机会。然而，可穿戴监测设备与皮肤长期接触的贴片舒适度一直是硬件的技术瓶颈。本研究报道了具有吸湿排汗和多机制粘附性能的仿生贴片，以实现对人体皮肤的适应性和舒适性。该贴片的设计基于锥形通孔和六角形微槽，可将汗液从皮肤定向输送到空气中，从而使贴片具有透气性能。通过分析具有芯吸结构机理的锥形通孔和六角形微槽，实验验证了仿生贴片的透气和排水能力。Ag/Ni微针阵列和PDMS-t粘附材料的多机制粘附保证了贴片信号采集的稳定性。本研究为增强贴片的透气性和适应性提供了一条新途径，以实现人体皮肤汗液条件下的生物电信号准确监测。

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Biomimetic Patch with Wicking-Breathable and Multi-mechanism Adhesion for Bioelectrical Signal Monitoring

Wearable bioelectrical monitoring devices can provide long-term human health information such as electrocardiogram and other physiological signals. It is a crucial part of the remote medical system. These can provide prediction for the diagnosis and treatment of cardiovascular disease and access to timely treatment. However, the patch comfort of the wearable monitoring devices in long-term contact with the skin have been a technical bottleneck of the hardware. In this study, the biomimetic patch with wicking-breathable and multi-mechanism adhesion performance to achieve adaptability and comfortability to human skin has been reported. The patch was designed based on a conical through-hole and hexagonal microgroove to directionally transport sweat from skin to air which gives the patch the breathable performance. The breathable and drainage capability of the biomimetic patch was experimentally verified by analyzing the conical through-hole and hexagonal microgroove with the structural mechanism of wicking. Multi-mechanism adhesion of the Ag/Ni microneedle array and PDMS-t adhesion material ensures the stability of patch signal acquisition. This study provides a new way for enhancing the breathability and adaptability of the patch to realize accurate bioelectrical signal monitoring under sweat conditions on human skin.

更新日期：2022-10-19

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