Nomenclature of HBV core protein-targeting antivirals,Nature Reviews Gastroenterology & Hepatology

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Nomenclature of HBV core protein-targeting antivirals
Nature Reviews Gastroenterology & Hepatology ( IF 45.9 ) Pub Date : 2022-10-07 , DOI: 10.1038/s41575-022-00700-z
Fabien Zoulim ₁ , Adam Zlotnick ₂ , Stephanie Buchholz ₃ , Eric Donaldson ₄ , John Fry ₅ , Anuj Gaggar ₆ , Jianming Hu ₇ , Michael Kann _{8,

9} , Oliver Lenz ₁₀ , Kai Lin ₁₁ , Nagraj Mani ₁₂ , Michael Nassal ₁₃ , William Delaney ₁₄ , Su Wang ₁₅ , Gabriel Westman ₁₆ , Veronica Miller ₁₇ , Harry L A Janssen _{18,

19}

Affiliation

Hepatology Department, INSERM Unit 1052, Hospices Civils de Lyon, Lyon University, Lyon, France.
Molecular and Cellular Biochemistry Department, Indiana University, Bloomington, IN, USA.
Federal Institute for Drugs and Medical Devices, BfArM, Bonn, Germany.
US Food and Drug Administration, Silver Spring, MD, USA.
Aligos Therapeutics, San Francisco, CA, USA.
Arrive Bio, San Francisco, CA, USA.
Department of Microbiology and Immunology, The Pennsylvania State University College of Medicine, Hershey, PA, USA.
Department of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Department of Clinical Microbiology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.
Janssen Pharmaceutica NV, Beerse, Belgium.
Aerium Therapeutics, Boston, MA, USA.
Arbutus Biopharma Inc., Department of Biology, Warminster, PA, USA.
Department of Medicine II, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Assembly Biosciences, South San Francisco, CA, USA.
Cooperman Barnabas Medical Center, RWJBarnabas-Rutgers Medical Group, Livingston, NJ, USA.
Swedish Medical Products Agency, Uppsala University, Uppsala, Sweden.
The Forum for Collaborative Research, Washington, DC, USA.
Department of Gastroenterology & Hepatology, Erasmus Medical Center, Rotterdam, Netherlands.
Toronto Centre for Liver Disease, University of Toronto, Ontario, Canada.

Hepatitis B virus (HBV) core protein-targeting compounds are in or entering clinical development without a standardized nomenclature. We propose a naming convention for these core-targeting antiviral products to provide clarity and accelerate HBV drug development.

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