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Recent developments in the synthesis of the isoquinoline-1,3(2H,4H)-dione by radical cascade reaction
Organic & Biomolecular Chemistry ( IF 2.9 ) Pub Date : 2022-09-21 , DOI: 10.1039/d2ob01554d
Yan-Ning Niu 1 , Xiao-Feng Xia 2
Affiliation  

In recent years, isoquinoline-1,3(2H,4H)-dione compounds have attracted extensive attention from synthetic chemists, with the aim of finding simple, mild, green and efficient synthetic methods. In this review, we summarize the diverse range of synthetic methods employing acryloyl benzamides as key substrates to furnish isoquinoline-1,3-diones using different radical precursors, such as those containing carbon, sulphur, phosphorus, nitrogen, silicon and bromine. This will stimulate the interest of readers to engage in research in this field.

中文翻译:

自由基级联反应合成异喹啉-1,3(2H,4H)-二酮的最新进展

近年来,异喹啉-1,3(2 H ,4 H )-二酮类化合物受到合成化学家的广泛关注,旨在寻找简单、温和、绿色、高效的合成方法。在这篇综述中,我们总结了使用丙烯酰苯甲酰胺作为关键底物的多种合成方法,使用不同的自由基前体(例如含有碳、硫、磷、氮、硅和溴的自由基前体)来提供异喹啉-1,3-二酮。这将激发读者从事该领域研究的兴趣。
更新日期:2022-09-21
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