Co-compartmentalization of Enzymes and Cofactors within Pickering Emulsion Droplets for Continuous-Flow Catalysis,Angewandte Chemie International Edition

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Co-compartmentalization of Enzymes and Cofactors within Pickering Emulsion Droplets for Continuous-Flow Catalysis
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2022-09-16 , DOI: 10.1002/anie.202211912
Wei Wei ₁ , Rammile Ettelaie ₂ , Xiaoming Zhang ₁ , Min Fan ₁ , Yue Dong ₁ , Zebiao Li ₃ , Hengquan Yang ₁

Affiliation

A continuous-flow biocatalytic system based on the co-compartmentalization of enzymes and cofactors within Pickering emulsion droplets has been developed. As exemplified by enzyme-catalyzed ketone enantioselective reduction and enantioselective transamination, this system features long-term operational stability, excellent catalytic efficiency and no need for exogenous cofactors.

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