A new, highly catalysis and stable liquid crystal 5CB-loaded nanogold (Au/5CB) nanosol was prepared through template method and was characterized in details. It was found that Au/5CB can strongly catalyze the new indicator reaction of fructose-Cu(II) tartrate complex to generate Cu₂O cube particles (CPs) with high resonance Rayleigh scattering effect. Combined the nanocatalytic amplification indicator reaction with the label-free aptamer (Apt) reaction, a new RRS aptasensing platform was developed to detect 0.05–1.0 ng mL⁻¹ oxytetracycline (OTC) and the limit of detection was 0.02 ng mL⁻¹. The developed RRS aptasensing platform can be also utilized to detect 7.5–60 ng mL⁻¹ malathion and 1–3.5 ng mL⁻¹ tetracyclines. Finally, the nanocatalytic reaction mechanism was studied.

采用模板法制备了一种新型、高催化、稳定的液晶负载5CB纳米金（Au/5CB）纳米溶胶，并对其进行了详细表征。发现Au/5CB可以强烈催化果糖-酒石酸Cu(II)络合物的新指示剂反应生成具有高共振瑞利散射效应的Cu _{2 O立方体颗粒(CPs)。}将纳米催化扩增指示剂反应与无标记适体（Apt）反应相结合，开发了一种新的RRS适体传感平台，可检测0.05-1.0 ng mL ^-1土霉素（OTC），检测限为0.02 ng mL ^-1。开发的 RRS 适配感应平台还可用于检测 7.5-60 ng mL ^-1马拉硫磷和 1-3.5 ng mL ^-1四环素。最后对纳米催化反应机理进行了研究。