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Imine Reductases: Multifunctional Biocatalysts with Varying Active Sites and Catalytic Mechanisms
ChemCatChem ( IF 3.8 ) Pub Date : 2022-09-12 , DOI: 10.1002/cctc.202200921
Kai Wu 1 , Junhai Huang 2 , Lei Shao 3
Affiliation  

Mechanisms: A comprehensive review of the catalytic mechanisms of imine reductase (IRED)-catalyzed imine reduction (IR), reductive amination (RA), recently reported conjugate reduction (CR), and stepwise CR-RA. Mechanistic insights from protein engineering were also included.

中文翻译:

亚胺还原酶:具有不同活性位点和催化机制的多功能生物催化剂

机制:全面回顾亚胺还原酶 (IRED) 催化的亚胺还原 (IR)、还原胺化 (RA)、最近报道的共轭还原 (CR) 和逐步 CR-RA 的催化机制。来自蛋白质工程的机制见解也包括在内。
更新日期:2022-09-12
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