Positive association of serum FUT8 activity with renal tubulointerstitial injury in IgA nephropathy patients,Immunity, Inflammation and Disease

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Positive association of serum FUT8 activity with renal tubulointerstitial injury in IgA nephropathy patients
Immunity, Inflammation and Disease ( IF 3.1 ) Pub Date : 2022-08-29 , DOI: 10.1002/iid3.686
Ning Yang _{1,

2} , Long-Kai Li ₂ , Hui He _{1,

2} , Xia-Nan Guo ₂ , Xue-Feng Yuan _{1,

2} , Zhi-Tong Li _{1,

2} , Wei-Dong Wang ₂ , Biao-Jie Qin ₂ , Xiang-Ning Du ₂ , Xu Zhang ₂ , Shu-Ni Chen ₂ , Hong-Li Lin ₂

Affiliation

α-1,6 Fucosyltransferase (FUT8) appears to play an essential role in the pathogenesis of renal fibrosis. However, it remained unknown whether FUT8 also contributed to renal fibrosis in immunoglobulin A nephropathy (IgAN). In the present study, we explored the association of serum FUT8 activity with renal tubulointerstitial injury in IgAN patients.

中文翻译：

IgA肾病患者血清FUT8活性与肾小管间质损伤呈正相关

α-1,6 岩藻糖基转移酶 (FUT8) 似乎在肾纤维化的发病机制中发挥重要作用。然而，目前尚不清楚 FUT8 是否也导致免疫球蛋白 A 肾病 (IgAN) 中的肾纤维化。在本研究中，我们探讨了 IgAN 患者血清 FUT8 活性与肾小管间质损伤的关系。

更新日期：2022-08-30

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