Adipic acid is an important building block of polymers, and is commercially produced by thermo-catalytic oxidation of ketone-alcohol oil (a mixture of cyclohexanol and cyclohexanone). However, this process heavily relies on the use of corrosive nitric acid while releases nitrous oxide as a potent greenhouse gas. Herein, we report an electrocatalytic strategy for the oxidation of cyclohexanone to adipic acid coupled with H₂ production over a nickel hydroxide (Ni(OH)₂) catalyst modified with sodium dodecyl sulfonate (SDS). The intercalated SDS facilitates the enrichment of immiscible cyclohexanone in aqueous medium, thus achieving 3.6-fold greater productivity of adipic acid and higher faradaic efficiency (FE) compared with pure Ni(OH)₂ (93% versus 56%). This strategy is demonstrated effective for a variety of immiscible aldehydes and ketones in aqueous solution. Furthermore, we design a realistic two-electrode flow electrolyzer for electrooxidation of cyclohexanone coupling with H₂ production, attaining adipic acid productivity of 4.7 mmol coupled with H₂ productivity of 8.0 L at 0.8 A (corresponding to 30 mA cm⁻²) in 24 h.

己二酸是聚合物的重要组成部分，通过酮醇油（环己醇和环己酮的混合物）的热催化氧化在商业上生产。然而，这个过程在很大程度上依赖于腐蚀性硝酸的使用，同时释放出一氧化二氮作为一种强效温室气体。在此，我们报告了一种将环己酮氧化为己二酸并在用十二烷基磺酸钠 (SDS) 改性的氢氧化镍 (Ni(OH) _{2 ) 催化剂上产生 H 2的电催化策略。嵌入的 SDS 促进了不混溶的环己酮在水介质中的富集，因此与纯 Ni(OH) 2}相比，己二酸的产率和法拉第效率 (FE) 提高了 3.6 倍（93% 对 56%）。该策略被证明对水溶液中的各种不混溶的醛和酮有效。此外，我们设计了一个实际的双电极流式电解槽，用于环己酮的电氧化与 H ₂生产耦合，在 24 小时内，在 0.8 A（对应于 30 mA cm ^-2）下，己二酸产率为 4.7 mmol，H ₂产率为 8.0 L。 H。