Eight new iridoids, jatavaleridoids A-H (1–8), were isolated from the roots and rhizomes of Valeriana jatamansi. Their structures and absolute configurations were elucidated based on NMR and HRESIMS spectroscopic data, as well as quantum chemical calculation. Structurally, compounds 1–5 and 8 were rare iridoids with long-chain fatty acid esters at C-10. In addition, compound 7 showed cytotoxicity, while compounds 1 and 2 exhibited inhibition on NO production.

中文翻译：

---

Jatavaleridoids AH，八种来自 Valeriana jatamansi Jones 根和根茎的新环烯醚萜

从Valeriana jatamansi的根和根茎中分离出八种新的环烯醚萜类化合物，jatavaleridoids AH ( 1-8 )。基于NMR和HRESIMS光谱数据以及量子化学计算阐明了它们的结构和绝对构型。在结构上，化合物1-5和8是稀有的环烯醚萜，在 C- 10处具有长链脂肪酸酯。此外，化合物7表现出细胞毒性，而化合物1和2表现出对 NO 产生的抑制作用。