Photocatalysis process is a promising technology for environmental remediation. In the continuous search of new heterogeneous photocatalysts, metal–organic frameworks (MOFs) have recently emerged as a new type of photoactive materials for water remediation. Particularly, titanium-based MOFs (Ti-MOFs) are considered one of the most appealing subclass of MOFs due to their promising optoelectronic and photocatalytic properties, high chemical stability, and unique structural features. However, considering the limited information of the reported studies, it is a hard task to determine if real-world water treatment is attainable using Ti-MOF photocatalysts. In this paper, via a screening with several Ti-MOFs, we originally selected and described the potential of a Ti-MOF in the photodegradation of a mixture of relevant Emerging Organic Contaminants (EOCs) in real water. Initially, two challenging drugs (i.e., the β-blocker atenolol (At) and the veterinary antibiotic sulfamethazine (SMT)) and four water stable and photoactive Ti-MOF structures have been rationally selected. From this initial screening, the mesoporous Ti-trimesate MIL-100(Ti) was chosen as the most promising photocatalyst, with higher At or SMT individual photodegradation (100% of At and SMT photodegradation in 2 and 4 h, respectively). Importantly, the safety of the formed by-products from the At and SMT photodegradation was confirmed. Finally, the At and SMT photodegradation capacity of MIL-100(Ti) was confirmed under realistic conditions, by using a mixture of contaminants in tap drinking water (100% of At and SMT photodegradation in 4 h), proven in addition its potential recyclability, which reinforces the potential of MIL-100(Ti) in water remediation.

光催化过程是一种很有前景的环境修复技术。在不断寻找新型异质光催化剂的过程中，金属有机框架（MOF）最近作为一种新型的水体修复光活性材料出现。特别是，钛基MOF（Ti-MOF）因其具有前景的光电和光催化性能、高化学稳定性和独特的结构特征而被认为是最有吸引力的MOF子类之一。然而，考虑到所报道的研究信息有限，确定使用 Ti-MOF 光催化剂是否可以实现现实世界的水处理是一项艰巨的任务。在本文中，通过对几种 Ti-MOF 的筛选，我们最初选择并描述了 Ti-MOF 在实际水中光降解相关新兴有机污染物 (EOC) 混合物的潜力。最初，合理选择了两种具有挑战性的药物（即β-受体阻滞剂阿替洛尔（At）和兽用抗生素磺胺二甲嗪（SMT））和四种水稳定性和光活性Ti-MOF结构。从初步筛选中，介孔 Ti-均苯三甲酸酯 MIL-100(Ti) 被选为最有前途的光催化剂，具有较高的 At 或 SMT 单独光降解能力（At 和 SMT 光降解分别在 2 小时和 4 小时内达到 100%）。重要的是，At 和 SMT 光降解所形成的副产物的安全性得到了证实。最后，通过使用自来水中的污染物混合物，在现实条件下证实了 MIL-100(Ti) 的 At 和 SMT 光降解能力（4 小时内 100% At 和 SMT 光降解），此外还证明了其潜在的可回收性，增强了 MIL-100(Ti) 在水体修复方面的潜力。