Our study was aimed to evaluate the postoperative outcomes of Mini Percutaneous Nephrolithotomy (Mini-PCNL) and Standard Percutaneous Nephrolithotomy (Standard-PCNL) to determine the optimum option for patients with renal calculi. For publications published between January 2010 and April 2021, a comprehensive search of the PubMed, Cochrane Library, Web of Science, and EMBASE databases was done. The literatures were chosen based on the criteria for inclusion and exclusion. After the data were retrieved and the quality was assessed, the meta-analysis was performed using Review Manager Software (RevMan 5.4.1, Cochrane Collaboration, Oxford, UK). We selected 20 trials with a total of 4953 people out of 322 studies. There were 2567 patients treated with Mini-PCNL and 2386 patients treated with Standard-PCNL. Meta-analysis results showed no difference in stone-free rates (SFR, P = 0.93), fever (P = 0.83), and postoperative pain (VAS score) (P = 0.21) between Mini-PCNL and Standard-PCNL. Patients in the Mini-PCNL group experienced shorter hospital stay (P < 0.0001), less hemoglobin drop (P < 0.00001), less blood transfusion (P < 0.00001), higher postoperative tubeless (P = 0.0002), and fewer complications including bleeding (P = 0.01), perforation (P = 0.03), and leakage (P = 0.01). Compared with Standard-PCNL, operative time was longer in the Mini-PCNL group (P = 0.0005). Mini-PCNL had a shorter hospital stay, less hemoglobin drop, less blood transfusion, greater postoperative tubeless, fewer complications, and a longer operational time when compared to Standard-PCNL. SFR, fever, and postoperative pain were similar in both of them. Mini-PCNL may be a superior option for patients with proper size renal calculi.

我们的研究旨在评估迷你经皮肾镜取石术 (Mini-PCNL) 和标准经皮肾镜取石术 (Standard-PCNL) 的术后结果，以确定肾结石患者的最佳选择。对于 2010 年 1 月至 2021 年 4 月期间发表的出版物，我们对 PubMed、Cochrane 图书馆、Web of Science 和 EMBASE 数据库进行了全面搜索。根据纳入和排除标准选择文献。在检索数据并评估质量后，使用 Review Manager 软件（RevMan 5.4.1，Cochrane Collaboration，Oxford，UK）进行荟萃分析。我们从 322 项研究中选择了 20 项试验，共有 4953 人参加。有 2567 名患者接受了 Mini-PCNL 治疗，2386 名患者接受了 Standard-PCNL 治疗。Mini-PCNL 和 Standard-PCNL 之间的P  = 0.93）、发热（P  = 0.83）和术后疼痛（VAS 评分）（P  = 0.21）。Mini-PCNL 组患者住院时间更短 ( P  < 0.0001)，血红蛋白下降更少 ( P  < 0.00001)，输血更少 ( P  < 0.00001)，术后无内胎率更高 ( P  = 0.0002)，出血等并发症更少 ( P  = 0.01)、穿孔 ( P  = 0.03) 和渗漏 ( P  = 0.01)。与 Standard-PCNL 相比，Mini-PCNL 组的手术时间更长（P = 0.0005）。与 Standard-PCNL 相比，Mini-PCNL 的住院时间更短，血红蛋白下降更少，输血更少，术后无内胎更多，并发症更少，手术时间更长。两者的 SFR、发热和术后疼痛相似。对于大小合适的肾结石患者，迷你 PCNL 可能是更好的选择。