In this work, a serial of Fe/Fe₃N based nanocomposites were synthesized by high-temperature pyrolytic method. Structural characterizations show that the small Fe/Fe₃N nanoparticles uniformly dispersed on the surface of carbon films, where thin carbon may effectively enhance the stability of Fe/Fe₃N and the carbon films can accelerate the migration of electrons. Moreover, Fe/Fe₃N based composite can significantly increase the effective area of bare GCE because of its high conductivity, large surface area, and good catalytic property. These structural advantages enhance the electrochemical performance of the constructed electrodes toward simultaneous dopamine (DA) and acetaminophen (AP) sensing. Under optimum condition, the linear ranges for DA and AP detection were 0.05–66.4 μM and 0.05–56.9 μM, respectively. In addition, due to its high sensitivity, good selectivity and strong stability, Fe/Fe₃N-900@GCE can also be applied for detecting DA and AP in real samples. This work provides a simple and effective strategy for constructing new electrode materials for small biomolecule sensing.

本工作采用高温热解法合成了一系列Fe/Fe _{3 N基纳米复合材料。}结构表征表明，细小的Fe/Fe ₃ N纳米颗粒均匀分散在碳膜表面，其中薄碳可以有效提高Fe/Fe ₃ N的稳定性，碳膜可以加速电子的迁移。此外，Fe/Fe ₃N基复合材料具有高导电性、大表面积和良好的催化性能，可以显着增加裸GCE的有效面积。这些结构优势增强了构建电极对同时多巴胺（DA）和对乙酰氨基酚（AP）传感的电化学性能。在最佳条件下，DA 和 AP 检测的线性范围分别为 0.05-66.4 μM 和 0.05-56.9 μM。此外，由于Fe/Fe ₃ N-900@GCE具有灵敏度高、选择性好、稳定性强等优点，还可用于检测实际样品中的DA和AP。这项工作为构建用于小生物分子传感的新电极材料提供了一种简单有效的策略。