The traditional preparation of MXeneTi₃C₂ is complicated. Two-dimensional MXeneTi₃C₂ nanosheets were prepared via in-situ generation of HF etching Ti₃AlC₂ under the microwave irradiation. Gold nanocluster doped nanosheets sol (MXene@Au) with excellent stability and strong catalysis was synthesized with no product residue reducer CO. MXene@Au nanosol can catalyze mandelic acid-HAuCl₄ to produce gold nanoparticles, which can be traced via resonance Rayleigh scattering (RRS) and surface-enhanced Raman scattering (SERS). Coupled the dual-mode nanocatalytic indicator reaction with aptamer reaction, a high sensitivity, selectivity, facile SERS/RRS dual-mode biosensnoring assay platform has been constructed for isocarbophos (ICP). The linear range of SERS was 1.0 × 10⁻³-2.5 × 10⁻² nmol/L, with a detection of limit 4.5 × 10⁻⁵ nmol/L (S/N = 3). It has been used to detect ICP in water samples, with a good recovery (95.5–104%) and a good relative standard deviation (5.2–9.6%). This new nanocatalytic amplification biosensoring strategy can also assay other organic pesticides including malathion, glyphosate, profenofos and carbendazim. In addition, the nanocatalytic mechanism was investigated.

MXeneTi ₃ C ₂的传统制备方法很复杂。通过在微波照射下原位产生HF蚀刻Ti ₃ AlC ₂制备二维MXeneTi ₃ C _{2纳米片。}在没有产物残留还原剂CO的情况下合成了具有优异稳定性和强催化作用的金纳米团簇掺杂纳米片溶胶(MXene@Au)。MXene@Au纳米溶胶可以催化扁桃酸-HAuCl ₄生产金纳米粒子，可以通过共振瑞利散射（RRS）和表面增强拉曼散射（SERS）进行追踪。将双模式纳米催化指示剂反应与适体反应相结合，构建了一个高灵敏度、高选择性、简便的SERS/RRS双模式生物传感检测平台。SERS的线性范围为1.0 × 10 ^-3 -2.5 × 10 ^-2  nmol/L，检测限为4.5 × 10 ^-5 nmol/L (S/N = 3)。它已用于检测水样中的 ICP，具有良好的回收率 (95.5–104%) 和良好的相对标准偏差 (5.2–9.6%)。这种新的纳米催化放大生物传感策略还可以检测其他有机农药，包括马拉硫磷、草甘膦、丙溴磷和多菌灵。此外，还研究了纳米催化机理。