Catalytic reduction of nitroarenes and unsaturated aldehydes to corresponding hydrogenated products is an environment-friendly technology to prepare industrially important intermediates. however, high chemoselectivity still remains a big challenge when a nitroarene or unsaturated aldehyde molecule with two or more reducible groups. Herein, we construct a novel confined catalyst by encapsulating Ag NPs into the nanospace of hierarchical hollow silica (SiO₂-Ag@void@SiO₂), enabling the excellent chemoselective hydrogenation (>99%) of 2-nitrochlorobenzene and cinnamyl aldehyde into corresponding amino groups (-NH₂) and hydroxyl groups (-OH) without hydrogenating other functional groups (-Cl and CC). The unique hydrogenation performance is identified to be associated with the confinement effect and highly dispersed Ag NPs because hydrogenation reaction takes place within the confined silver nanospace. Therefore, our study provides a guide to construct highly active catalysts for chemoselective catalysis.

硝基芳烃和不饱和醛催化还原为相应的氢化产物是制备工业上重要的中间体的环保技术。然而，当硝基芳烃或不饱和醛分子具有两个或多个可还原基团时，高化学选择性仍然是一个很大的挑战。在此，我们通过将 Ag NPs 封装在分级空心二氧化硅 (SiO ₂ -Ag@void@SiO ₂ ) 的纳米空间中构建了一种新型的受限催化剂，使 2-硝基氯苯和肉桂醛的化学选择性氢化 (>99%) 成为相应的氨基 (-NH ₂ ) 和羟基 (-OH) 不氢化其他官能团 (-Cl 和 CC）。独特的加氢性能被认为与限制效应和高度分散的 Ag NPs 相关，因为加氢反应发生在受限的银纳米空间内。因此，我们的研究为构建用于化学选择性催化的高活性催化剂提供了指导。