The abuse of antibiotics has serious side effects on human health, which makes its detection particularly important. A novel three-dimensional Cd-MOF [Cd(H₂L)(H₂O)]_n (H₂L = 1,4-bis (2-methylimidazol-1-yl) terephthalic acid) } is successfully synthesized by solvothermal method with Cd(ClO₄)₂·6H₂O and H₂L. Further in aqueous solution using Cd-MOF as fluorescence sensor detects of nitrofuran antibiotics. The results show that the Cd-MOF can detect antibiotics with high selectivity and high sensitivity. The K_sv values were calculated as 1.96 × 10^-4 M⁻¹ and 1.13 × 10^-4 M⁻¹ for nitrofurantoin (NFT) and nitrofurancillin (NFZ). The limit of detections (LODs) of Cd-MOF were 0.15 nM for NFT and 0.29 nM for NFZ. Furthermore, bimodal self-calibration detection is more accurate than unimodal detection and this research provides a reliable basis for the application of MOF in the field of fluorescence detection.

滥用抗生素对人体健康有严重的副作用，这使得其检测尤为重要。溶剂热法成功合成了一种新型三维Cd-MOF [Cd(H ₂ L)(H ₂ O)] _n (H ₂ L = 1,4-bis (2-methylimidazol-1-yl) terephthalic acid)}用Cd(ClO ₄ ) ₂ ·6H ₂ O和H ₂ L的方法。进一步在水溶液中用Cd-MOF作为荧光传感器检测硝基呋喃类抗生素。结果表明，Cd-MOF可以高选择性、高灵敏度地检测抗生素。K _sv值计算为 1.96 × 10 ^-4 M ^-1呋喃妥因 (NFT) 和呋喃西林 (NFZ) 为1.13 × 10 ^-4 M ^{-1 。}NFT 的 Cd-MOF 检测限 (LOD) 为 0.15 nM，NFZ 为 0.29 nM。此外，双峰自校准检测比单峰检测更准确，本研究为MOF在荧光检测领域的应用提供了可靠依据。