A new Bi-naphthylated oxacalix[4]arene viz. BNOC has been designed and synthesized as a potential fluorescence probe for selective recognition of 4-NT and 2,3-DNT compared to the other nitroaromatic compounds due to the geometry and hydrophobicity of the modified cavity. The interaction of BNOC with 4-NT and 2,3-DNT is confirmed by ESI-MS study. A highly sensitive dual-signaling electrochemical detection based on host-guest interaction between BNOC as signal probe and 4-NT, 2,3-DNT as target molecules was developed. The LOD for 4-NT and 2,3-DNT was determined to be 34.1 nM and 36.7 nM respectively. The concentration of 2,3-DNT and 4-NT in the water sample was determined using a standard addition procedure. Computational calculation further indicates that strong π-π interaction between host BNOC and guest NACs executes selective sensing of 4-NT and 2,3DNT.

一种新的双萘基化 oxacalix[4] 芳烃即。由于修饰空腔的几何形状和疏水性，与其他硝基芳族化合物相比，BNOC 已被设计和合成为一种潜在的荧光探针，用于选择性识别 4-NT 和 2,3-DNT。ESI-MS 研究证实了 BNOC 与 4-NT 和 2,3-DNT 的相互作用。开发了一种基于BNOC作为信号探针和4-NT、2,3-DNT作为靶分子的主客体相互作用的高灵敏度双信号电化学检测方法。4-NT 和 2,3-DNT 的 LOD 分别确定为 34.1 nM 和 36.7 nM。使用标准添加程序测定水样中 2,3-DNT 和 4-NT 的浓度。