Dabigatran is an anticoagulant with potential use during cardiopulmonary bypass in children and adults. The pharmacokinetic–pharmacodynamic relationship for dabigatran anticoagulation effect was investigated in an intact animal model using rabbits.

中文翻译：

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达比加群抗凝的延迟浓度效应模型

达比加群是一种抗凝剂，在儿童和成人体外循环中具有潜在用途。在使用兔的完整动物模型中研究了达比加群抗凝作用的药代动力学-药效学关系。