The inverted scanning microwave microscope (iSMM) is a recently developed variety of scanning microprobe microscopes. Similar to a scanning microwave microscope (SMM), the iSMM is sensitive to not only surface structure, but also electromagnetic properties below the surface. Different from the SMM, the iSMM can be converted from any scanning probe microscope, such as an atomic force microscope (AFM) and a scanning tunneling microscope, with a simple metal probe to outperform the SMM in terms of ruggedness, bandwidth, sensitivity, and dynamic range. This letter reports the first iSMM images of a vital mitochondrion in an isotonic glucose solution. Compared to the AFM and SMM, the iSMM offers more insights into the mitochondrion. This shows the potential of iSMM for noninvasive and label-free imaging and characterization of subcellular structures.

中文翻译：

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液体中重要线粒体的倒置扫描微波显微镜


倒置扫描微波显微镜（iSMM）是最近开发的一种扫描微探针显微镜。与扫描微波显微镜 (SMM) 类似，iSMM 不仅对表面结构敏感，而且对表面以下的电磁特性敏感。与SMM不同的是，iSMM可以由任何扫描探针显微镜（例如原子力显微镜（AFM）和扫描隧道显微镜）转换而来，用简单的金属探针在坚固性、带宽、灵敏度和灵敏度方面优于SMM。动态范围。这封信报道了等渗葡萄糖溶液中重要线粒体的第一张 iSMM 图像。与 AFM 和 SMM 相比，iSMM 提供了更多关于线粒体的见解。这显示了 iSMM 在非侵入性、无标记成像和亚细胞结构表征方面的潜力。