The synthesis of a new 4-[2-(1-methyl-1H-imidazol-2-ylsulfanyl)-acetylamino]-benzenesulfonic acid from available reagents using an efficient strategy was reported, and its antimicrobial ability against bacterial strains was investigated. This new compound was characterised using a single crystal technique, which showed that the compound crystallised with a monoclinic system in a P21/c space group. Its unit-cell parameters were a = 17.0692 (2) Å, b = 5.0326 (3) Å, c = 17.2979 (4) Å, β = 106.596° (2) and Z = 4. Crystal packing was stabilised by hydrogen bonds, pi- stacking, C-H….pi and van der Waals interactions. The intermolecular interaction analysis of the crystal structure was affected by Hirschfeld surface analysis, and associated two-dimensional fingerprint plots were utilised. In addition, docking investigations of the biological activity of the synthesised compound was also performed.

报道了使用有效策略从现有试剂合成新的 4-[2-(1-methyl-1H-imidazol-2-ylsulfanyl)-acetylamino]-苯磺酸，并研究了其对细菌菌株的抗菌能力。使用单晶技术对这种新化合物进行了表征，表明该化合物在 P21/c 空间群中以单斜晶系结晶。其晶胞参数为a  = 17.0692 (2) Å, b  = 5.0326 (3) Å, c  = 17.2979 (4) Å, β  = 106.596° (2) 和Z = 4. 晶体堆积通过氢键、pi 堆积、CH….pi 和范德华相互作用稳定。晶体结构的分子间相互作用分析受到 Hirschfeld 表面分析的影响，并使用了相关的二维指纹图。此外，还对合成化合物的生物活性进行了对接研究。