The sugars will eventually be exported transporters (SWEETs) are a unique class of membrane-bound sugar transporters that not only take part in hexose and sucrose transport across the biological membranes but also are involved in diverse physiological functions in plants. Although the role of SWEETs in biotic stress response is well documented, their involvement in plant’s response to abiotic and heavy metal (loid) stress is poorly understood. Thus, to bridge this gap, a comprehensive in silico study of the OsSWEET family was conducted in rice. A total of 21 OsSWEET members showing elaborate gene duplications were identified. Interestingly, the promoter cis-regulatory element and miRNA target analyses indicated the possible regulation of OsSWEETs during abiotic and heavy metal (loid) stresses. In-silico gene expression analysis further validated the involvement of OsSWEET transporters in abiotic and heavy metal (loid) stress responses in rice plants. Moreover, the protein-protein interaction analysis indicated their possible interactions with some well-known rice heavy metal transporter proteins. Taken together, this is the first comprehensive analysis of the involvement of OsSWEETs in abiotic, especially heavy metal (loid) stress responses in rice plants that necessitate further experimental studies to understand the mode of action and regulatory mechanisms of these transporters in heavy metal (loid) stress.

糖最终将成为输出转运蛋白( SWEETs ) 是一类独特的膜结合糖转运蛋白，不仅参与己糖和蔗糖跨生物膜的转运，而且还参与植物的多种生理功能。尽管 SWEETs 在生物胁迫反应中的作用已有充分的记载，但它们在植物对非生物和重金属 (loid) 胁迫反应中的作用却知之甚少。因此，为了弥补这一差距，在水稻中对 OsSWEET 家族进行了全面的计算机研究。共鉴定了 21 个显示复杂基因重复的 OsSWEET 成员。有趣的是，启动子cis- 调控元件和 miRNA 靶点分析表明OsSWEETs在非生物和重金属 (loid) 胁迫期间可能受到调控。计算机基因表达分析进一步验证了 OsSWEET 转运蛋白参与水稻植物的非生物和重金属 (loid) 胁迫反应。此外，蛋白质-蛋白质相互作用分析表明它们可能与一些著名的水稻重金属转运蛋白相互作用。综上所述，这是首次全面分析 OsSWEETs 参与非生物，特别是水稻植物中的重金属 (loid) 胁迫反应，需要进一步的实验研究以了解这些转运蛋白在重金属 (loid) 中的作用模式和调控机制。 ） 压力。