The existence of a female phenotype profile in autistic spectrum disorder is one of the current hypotheses to explain the diagnostic discrepancy between men and women. In this context, an international literature review was carried out to evidence and describe the characteristics of restricted interests found in girls with autistic spectrum disorder. A documentary search was conducted on PubMed and a systematic literature review was carried out based on the PRISMA methodology. We selected studies with a population of boys and girls diagnosed as autistic according to the DSM-IV or the DSM-5, in which quantitative and descriptive comparisons of restricted interests, according to gender were carried out. Nineteen studies were found to be relevant. Fifteen enabled a refining of the characteristics of restricted interests among females: fewer restricted interests were identified in comparison with boys, and the autistic girls’ interests seem to be closer to those of neurotypical girls than to those of autistic boys, which thus led to more complex screening. Age and Intelligence quotient seem to be two factors that trigger variations in restricted interests differently according to gender. Representations among professionals also have an impact on diagnoses among girls. For future research, one of the perspectives could be a comparison between girls with autism and neurotypical girls to limit gender bias. The present results contribute to potentially extending knowledge of a female phenotypical profile in autism and show the need to improve the general population’s awareness, to improve health professionals’ training and possibly to revise the diagnostic tools.

自闭症谱系障碍中女性表型的存在是解释男性和女性之间诊断差异的当前假设之一。在此背景下，进行了一项国际文献综述，以证明和描述患有自闭症谱系障碍的女孩的兴趣受限的特征。在PubMed上进行文献检索，并基于PRISMA方法进行系统文献综述。我们选择了根据 DSM-IV 或 DSM-5 诊断为自闭症的男孩和女孩群体的研究，其中根据性别对受限兴趣进行了定量和描述性比较。发现十九项研究是相关的。十五项研究对女性限制性兴趣的特征进行了细化：与男孩相比，发现的限制性兴趣较少，自闭症女孩的兴趣似乎更接近神经正常女孩的兴趣，而不是自闭症男孩的兴趣，从而导致更多复杂的筛选。年龄和智商似乎是根据性别不同引发不同兴趣限制变化的两个因素。专业人士的代表也会对女孩的诊断产生影响。对于未来的研究，视角之一可能是对自闭症女孩和神经正常女孩进行比较，以限制性别偏见。目前的结果有助于潜在地扩展对自闭症女性表型特征的了解，并表明需要提高普通大众的认识，改善卫生专业人员的培训，并可能修改诊断工具。