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Cerium(III) triflate–catalyzed cycloaddition reaction in aqueous conditions to substituted naphthotriazolediones
Journal of the Chinese Chemical Society ( IF 1.6 ) Pub Date : 2022-05-14 , DOI: 10.1002/jccs.202200018
Ya-Syuan Li, Chien-Fu Liang

In this study, the cerium(III) trifluoromethanesulfonate–catalyzed cycloaddition of 1,4-naphthoquinone with functionalized azides in aqueous solutions was used to synthesize naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives. Moreover, our method boasts scalability and completes the synthesis of two key biological compounds. Our method's advantages are environmentally friendly reaction conditions, easy applicability in large-scale operations, broad structurally diverse products produced in high yields, and the recyclability of catalysts.

中文翻译:

三氟甲磺酸铈 (III) 催化水性条件下取代萘三唑二酮的环加成反应

本研究采用三氟甲磺酸铈(III)催化的 1,4-萘醌与官能化叠氮化物在水溶液中的环加成反应合成萘并[2,3 - d ][1,2,3]三唑-4,9-二酮衍生物。此外,我们的方法具有可扩展性并完成了两种关键生物化合物的合成。我们的方法的优点是环境友好的反应条件,易于大规模操作,高产率生产的结构多样的产品,以及催化剂的可回收性。
更新日期:2022-05-14
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