Traditional photoelectrochemical (PEC) systems with inorganic semiconductors as photoactive materials generally involve effortless recombination of electron-hole pairs, which greatly limit the detection sensitivity. The arrangement of multiple components with tunable bandgaps provides an effective way to accelerate charge transfer. In this work, a framework material with adjustable structure was used to promote the charge transfer in the PEC process. The framework was constructed with 9,10-di(p-carboxyphenyl)anthracene (DPA) ligands as the light collector to coordinate with Zn²⁺ nodes, which formed an electronegative metal-organic framework (ZnMOF), and showed good conductivity and PEC performance due to the π-π stacking of DPA and the intrareticular charge transfer. Based on the band and charge matching of dopamine (DA) with ZnMOF, the ZnMOF modified electrode as a biosensor showed excellent PEC response to DA with good selectivity, thus realized sensitive detection of DA ranging from 0.03 to 10 μM with a detection limit of 17.7 nM. The biosensor could be used to monitor the release of DA from PC12 cells and evaluate the stimulation of K⁺ to DA release. The conductive framework material provided an approach to develop highly selective sensing platform for trace bioanalysis.

以无机半导体作为光活性材料的传统光电化学（PEC）系统通常涉及电子-空穴对的轻松重组，这极大地限制了检测灵敏度。具有可调带隙的多个组件的排列提供了一种加速电荷转移的有效方法。在这项工作中，一种结构可调的框架材料被用来促进 PEC 过程中的电荷转移。该框架以 9,10-二(对羧基苯基)蒽 (DPA) 配体作为光收集器与 Zn ^{2+配位构建}结，形成电负性金属有机框架（ZnMOF），由于DPA的π-π堆积和网状内电荷转移，表现出良好的导电性和PEC性能。基于多巴胺（DA）与ZnMOF的能带和电荷匹配，作为生物传感器的ZnMOF修饰电极对DA表现出优异的PEC响应和良好的选择性，从而实现了DA在0.03~10 μM范围内的灵敏检测，检测限为17.7纳米。该生物传感器可用于监测 DA 从 PC12 细胞中的释放，并评估 K ⁺对 DA 释放的刺激。导电框架材料提供了一种开发用于痕量生物分析的高选择性传感平台的方法。