HIVEP3 cooperates with ferroptosis gene signatures to confer adverse prognosis in acute myeloid leukemia,Cancer Medicine

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HIVEP3 cooperates with ferroptosis gene signatures to confer adverse prognosis in acute myeloid leukemia
Cancer Medicine ( IF 2.9 ) Pub Date : 2022-05-10 , DOI: 10.1002/cam4.4806
Xiaoning Zhang ₁ , Xiaoyu Zhang ₂ , Kuo Liu ₁ , Wenwen Li ₁ , Jiazheng Wang ₁ , Peng Liu ₁ , Wanshan Ma ₁

Affiliation

The human immunodeficiency virus type I enhancer binding protein (HIVEP) family, which contains zinc finger and acid-rich (ZAS) domains, has been demonstrated to be implicated in vital biological processes, such as cell survival, tumor necrosis factor (TNF) signaling, and tumor formation. However, its expression patterns, prognostic relevance, and functional implications in acute myeloid leukemia (AML) remain elusive.

中文翻译：

HIVEP3 与 ferroptosis 基因特征合作赋予急性髓系白血病不良预后

人类免疫缺陷病毒 I 型增强子结合蛋白 ( HIVEP ) 家族包含锌指和富酸 (ZAS) 结构域，已被证明与重要的生物学过程有关，例如细胞存活、肿瘤坏死因子 (TNF) 信号传导和肿瘤形成。然而，其在急性髓性白血病 (AML) 中的表达模式、预后相关性和功能意义仍然难以捉摸。

更新日期：2022-05-10

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